Ongoing Projects

36 ongoing research projects. Click any project to see full details.

S/N	Project Title	NIMR Lead	Lead Centre
1	Severe Malaria treatment with Rectal artesunate and Artemisinin-based Combination Therapy [in r…	Vito Baraka	NIMR Tanga
Full title Severe Malaria treatment with Rectal artesunate and Artemisinin-based Combination Therapy [in remote settings]. (Acronym: SEMA ReACT). NIMR Lead Vito Baraka Lead Centre NIMR Tanga Funder EDCTP3 NIMR Budget €231,645.00 Funding Duration 04/2023 to 03/2027
2	Climate Change and its Adverse Effects on the double burden of Malnutrition and Infectious Dise…	Daniel Minja	NIMR Tanga
Full title Climate Change and its Adverse Effects on the double burden of Malnutrition and Infectious Diseases among women of reproductive age in northeastern Tanzania NIMR Lead Daniel Minja Lead Centre NIMR Tanga Funder Danida NIMR Budget DKK 3,000,000 Funding Duration 01/2024 to 12/2027
3	Medical and Environmental Anthropology for 21st Century East Africa	Peter Mangesho	NIMR Amani
Full title Medical and Environmental Anthropology for 21st Century East Africa NIMR Lead Peter Mangesho Lead Centre NIMR Amani Funder NORAD NIMR Budget Norwegian Krone 20,000,000 Funding Duration Jan 2021 – Dec 2026.
4	“Chanjo Kwa Wakati” – Leveraging community health workers and a responsive digital health syste…	Esther Ngadaya	NIMR Muhimbili
Full title “Chanjo Kwa Wakati” – Leveraging community health workers and a responsive digital health system to improve vaccination coverage and timeliness in resource-limited settings NIMR Lead Esther Ngadaya Lead Centre NIMR Muhimbili Funder U.S. National Institutes of Health (NIH) NIMR Budget USD 888,769 Funding Duration September 2022 to September 2027
5	The African Cohort study	Lucas Maganga	NIMR Mbeya
Full title The African Cohort study NIMR Lead Lucas Maganga Lead Centre NIMR Mbeya Funder US Military HIV Research Program/WRAIR NIMR Budget USD 850,000 annually Funding Duration 2013-2027
6	A randomized double-blind placebo-controlled trial of Rifapentine and Isoniazid for prevention …	Elias Nyanda	NIMR Mbeya
Full title A randomized double-blind placebo-controlled trial of Rifapentine and Isoniazid for prevention of Tuberculosis in people with diabetes NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder EDCTP NIMR Budget Euro 1,374,830 Funding Duration Jan 2020 – Dec 2027
7	Platform Assessing Regimens And Durations In a Global Multisite consortium for TB A Seamless Ph…	Elias Nyanda	NIMR Mbeya
Full title Platform Assessing Regimens And Durations In a Global Multisite consortium for TB A Seamless Phase 2B/2C Platform Trial to Evaluate Multiple Regimens and Durations of Treatment in Pulmonary Tuberculosis NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder H2020 (IMI) NIMR Budget per patient Euro 14,400 Funding Duration 2023 - 2028
8	East Africa International Epidemiology Database to evaluate AIDS (IeDEA)	Paul Kazyoba	NIMR Mabibo
Full title East Africa International Epidemiology Database to evaluate AIDS (IeDEA) NIMR Lead Paul Kazyoba Lead Centre NIMR Mabibo Funder NIH through Indiana University NIMR Budget — Funding Duration —
9	Learning Initiative on Norms, Exploitation and Abuse (LINEA) Trial Evaluation of a Complex Inte…	Joyce Wamoyi	NIMR Mwanza
Full title Learning Initiative on Norms, Exploitation and Abuse (LINEA) Trial Evaluation of a Complex Intervention to Prevent Age-disparate Transactional Sex in Tanzania NIMR Lead Joyce Wamoyi Lead Centre NIMR Mwanza Funder OAK foundation, UK NIMR Budget $ 500,000 Funding Duration July 2022- Dec 2026
10	HIV, Sleep, Nocturnal Non-Dipping, and Cardiovascular Disease: a Tanzanian Cohort (HIV&HTN Slee…	Saidi Kapiga	NIMR Mwanza
Full title HIV, Sleep, Nocturnal Non-Dipping, and Cardiovascular Disease: a Tanzanian Cohort (HIV&HTN Sleep Study) NIMR Lead Saidi Kapiga Lead Centre NIMR Mwanza Funder US National Institutes of Health NIMR Budget $902,633 Funding Duration 2021 - 2026
11	Comparisons in Genital Mucosal Immune Cell Populations, Gene Expression, and Impaired Anti-Vira…	John Changalucha	NIMR Mwanza
Full title Comparisons in Genital Mucosal Immune Cell Populations, Gene Expression, and Impaired Anti-Viral Immunity in Women with and without Female Genital Schistosomiasis before and after Praziquantel Treatment NIMR Lead John Changalucha Lead Centre NIMR Mwanza Funder US National Institutes of Health / National Institute of Allergy and Infectious Diseases NIMR Budget $1,099,777 Funding Duration 2022 - 2027
12	Engaging Religious Leaders to reduce blood pressures in Tanzanian communities	Bazil Kavishe	NIMR Mwanza
Full title Engaging Religious Leaders to reduce blood pressures in Tanzanian communities NIMR Lead Bazil Kavishe Lead Centre NIMR Mwanza Funder National Institutes of Health/National Heart, Lung, and Blood Institute NIMR Budget $1,093,833 Funding Duration January 2022 - December 2026
13	Improving BrightSAM study management of malnutrition to support child development in the contex…	George PrayGod	NIMR Mwanza
Full title Improving BrightSAM study management of malnutrition to support child development in the context of climate change: the BrightSAM study NIMR Lead George PrayGod Lead Centre NIMR Mwanza Funder The Danish Ministry of Foreign Affairs NIMR Budget DKK 8,287,405 Funding Duration June 2023 to May 2028
14	The impact of a variable climate on long-term adverse health effects in Tanzania	George PrayGod	NIMR Mwanza
Full title The impact of a variable climate on long-term adverse health effects in Tanzania NIMR Lead George PrayGod Lead Centre NIMR Mwanza Funder The Danish Ministry of Foreign Affairs. NIMR Budget DKK 8,472,224 Funding Duration June 2023 to May 2028
15	A phase 2, partially-blinded, randomised trial assessing the safety and efficacy of TBAJ876 or …	Elias Nyanda	NIMR Mbeya
Full title A phase 2, partially-blinded, randomised trial assessing the safety and efficacy of TBAJ876 or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis. NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder Tb Alliance. NIMR Budget 15,000£ per participant. Funding Duration —
16	Increasing Neonatal HIV Test and Treat to Maximize the Long-Term Impact on Infant Health and No…	Issa Sabi	NIMR Mbeya
Full title Increasing Neonatal HIV Test and Treat to Maximize the Long-Term Impact on Infant Health and Novel Infant Antiretroviral Treatment NIMR Lead Issa Sabi Lead Centre NIMR Mbeya Funder EDCTP NIMR Budget € 1,371,000 Funding Duration 2023-2026
17	Post TB Lung Disease: Assessing long term morbidity and mortality and associated risk factors	Elias Nyanda	NIMR Mbeya
Full title Post TB Lung Disease: Assessing long term morbidity and mortality and associated risk factors NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder BMBF NIMR Budget € 1,424,175.16 Funding Duration 2024 - 2027
18	Developing national and global agendas for the ethics of post-trial arrangements in low-middle …	Sia Malekia	NIMR Muhimbili
Full title Developing national and global agendas for the ethics of post-trial arrangements in low-middle income countries during pandemics/epidemics (Short title: Pandemic Ethics) Multi-country study GLOBVAC 3363383 NIMR Lead Sia Malekia Lead Centre NIMR Muhimbili Funder Research Council of Norway NIMR Budget NOK 910,000 Funding Duration September 2023 to August 2027
19	Co-designing neglected zoonosis intervention through One Health, education, and public-private …	John Kunda	NIMR Muhimbili
Full title Co-designing neglected zoonosis intervention through One Health, education, and public-private partnership NIMR Lead John Kunda Lead Centre NIMR Muhimbili Funder JICA NIMR Budget US $ 1M Funding Duration June 2024 to July 2028
20	A randomized, open-label, multicenter study to compare efficacy, safety and tolerability of KLU…	Vito Baraka	NIMR Tanga
Full title A randomized, open-label, multicenter study to compare efficacy, safety and tolerability of KLU156 with Coartem® in the treatment of uncomplicated Plasmodium falciparum malaria in adults and children ≥ 5 kg body weight followed by an extension phase with repeated KLU156 treatment. ACRONYM: KALUMA NIMR Lead Vito Baraka Lead Centre NIMR Tanga Funder Novartis South Africa (Pty) Ltd. NIMR Budget $450,608 Funding Duration January 2024 to October 2027
21	After the Single Use: Rethinking medical devices for reuse, renewal, and resilience	Peter Mangesho	NIMR Amani
Full title After the Single Use: Rethinking medical devices for reuse, renewal, and resilience NIMR Lead Peter Mangesho Lead Centre NIMR Amani Funder Wellcome Trust NIMR Budget 5,899,960 £ Funding Duration 2024-2029
22	An Open-label Extension Study to Evaluate the Long-term Safety of Inclacumab Administered to Pa…	Issa Sabi	NIMR Mbeya
Full title An Open-label Extension Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants with Sickle Cell Disease Who Have Participated in an Inclacumab Clinical Trial. NIMR Lead Issa Sabi Lead Centre NIMR Mbeya Funder Global Blood Therapeutics, Inc. whole owned by Pfizer NIMR Budget 21,822.70 per patient per 22 visits Funding Duration —
23	Bringing Innovation to cLinical and Laboratory research to end HIV/AIDS In Africa through New v…	Elias Nyanda	NIMR Mbeya
Full title Bringing Innovation to cLinical and Laboratory research to end HIV/AIDS In Africa through New vaccine Technology (BRILLIANT) NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder USAID NIMR Budget USD 368,975 Funding Duration 2024-2028
24	The epidemiology of syphilis in Tanzania, are we overlooking yaws?	Clara Lubinza	NIMR Muhimbili
Full title The epidemiology of syphilis in Tanzania, are we overlooking yaws? NIMR Lead Clara Lubinza Lead Centre NIMR Muhimbili Funder Bill and Melinda Gates Foundation NIMR Budget EURO 25,000 Funding Duration 1.5 years
25	Baseline entomological surveys and community engagement at selected transmission zero study sit…	Alphaxard Manjurano	NIMR Mwanza
Full title Baseline entomological surveys and community engagement at selected transmission zero study sites, in Ukerewe Tanzania NIMR Lead Alphaxard Manjurano Lead Centre NIMR Mwanza Funder Bill and Melinda Gates Foundation through Imperial College of Science, Technology and Medicine NIMR Budget USD 732,039 Funding Duration January 2024 – December 2026
26	Strengthening health information systems to adequately capture snakebite-envenoming data from c…	Paul Kazyoba	NIMR Mabibo
Full title Strengthening health information systems to adequately capture snakebite-envenoming data from communities and health facilities. NIMR Lead Paul Kazyoba Lead Centre NIMR Mabibo Funder — NIMR Budget — Funding Duration —
27	Characterization of mosquito larvae habitats, abundance and species composition in Eastern same…	Said Frank Magogo	NIMR Amani
Full title Characterization of mosquito larvae habitats, abundance and species composition in Eastern same, northeastern Tanzania NIMR Lead Said Frank Magogo Lead Centre NIMR Amani Funder — NIMR Budget — Funding Duration —
28	Early detection and characterization of Drug resistance Tuberculosis to Inform Clinical Managem…	Bariki Mtafya	NIMR Mbeya
Full title Early detection and characterization of Drug resistance Tuberculosis to Inform Clinical Management of the Patients Treatment in Routine Healthcare Settings NIMR Lead Bariki Mtafya Lead Centre NIMR Mbeya Funder UNESCO-TWAS NIMR Budget $60,000 Funding Duration 2024-2026
29	Global Burden Estimation of Human Papillomavirus Infections	Saidi Kapiga	NIMR Mwanza
Full title Global Burden Estimation of Human Papillomavirus Infections NIMR Lead Saidi Kapiga Lead Centre NIMR Mwanza Funder Bill and Melinda Gates Foundation NIMR Budget $865,000 Funding Duration 2023-2027
30	Diagnostic Performance of GeneXpert MTB/RIF and Line Probe Assays in the Detection of Multidrug…	Rehema Simbauranga	NIMR Muhimbili
Full title Diagnostic Performance of GeneXpert MTB/RIF and Line Probe Assays in the Detection of Multidrug Resistance TB in Tanzania (Di-MDR) NIMR Lead Rehema Simbauranga Lead Centre NIMR Muhimbili Funder EACCR 3 NIMR Budget TZS 25,000,000 Funding Duration 1 year
31	The DELIVER consortium - Developing Leadership and Innovation for Viral Eradication Research	Elias Nyanda	NIMR Mbeya
Full title The DELIVER consortium - Developing Leadership and Innovation for Viral Eradication Research NIMR Lead Elias Nyanda Lead Centre NIMR Mbeya Funder US-MHRP NIMR Budget $2,181,039.48 Funding Duration 2024-2029
32	Implementing wastewater and environmental surveillance for Mpox in Sub-Saharan Africa	Vito Baraka	NIMR Tanga
Full title Implementing wastewater and environmental surveillance for Mpox in Sub-Saharan Africa NIMR Lead Vito Baraka Lead Centre NIMR Tanga Funder — NIMR Budget 175,000 EUR Funding Duration 2 years
33	Guided for lymphedema management to improve quality of life in established patient cohorts with…	Akili Kalinga	NIMR Headquarters
Full title Guided for lymphedema management to improve quality of life in established patient cohorts with filarial Lymphedema. NIMR Lead Akili Kalinga Lead Centre NIMR Headquarters Funder Federal Germany Ministry of Education and Research NIMR Budget Euro 25,000 Funding Duration Jan 2023–Dec 2027
34	The use of digital tools for morbidity management of lymphatic filariasis in endemic regions in…	Akili Kalinga	NIMR Headquarters
Full title The use of digital tools for morbidity management of lymphatic filariasis in endemic regions in Tanzania NIMR Lead Akili Kalinga Lead Centre NIMR Headquarters Funder Federal Germany Ministry of Education and Research NIMR Budget Euro 20,600 Funding Duration Jan 2023–Dec 2027
35	Alternative strategies to accelerate the elimination of LF and Onchocerciasis transmission in T…	Akili Kalinga	NIMR Headquarters
Full title Alternative strategies to accelerate the elimination of LF and Onchocerciasis transmission in Tanzania. NIMR Lead Akili Kalinga Lead Centre NIMR Headquarters Funder Federal Germany Ministry of Education and Research NIMR Budget Euro 17,500 Funding Duration Jan 2023–Dec 2027
36	Test and Treat of infected individuals for lymphatic filariasis hotspot clusters in endemic dis…	Winifrida John	NIMR Headquarters
Full title Test and Treat of infected individuals for lymphatic filariasis hotspot clusters in endemic districts Tanzania NIMR Lead Winifrida John Lead Centre NIMR Headquarters Funder Federal Germany Ministry of Education and Research NIMR Budget Euro 22,000 Funding Duration Jan 2023–Dec 2027